EurekAlert!

Single-cell profiling identifies reward behavior-related neurons and alterations in the ventral tegmental area based on Arvcf-knockout mouse model

The ventral tegmental area (VTA) is a key brain region for dopamine production and the regulation of reward-related behaviors. While dopaminergic neurons have traditionally been considered the primary ...
Kaleido Scope

Jeremy Day Probes Reward Signaling in the Brain

As an undergraduate at Auburn University in the early 2000s, Jeremy Day was thinking of becoming an architect. But an opportunity to work on a research project investigating reward learning in rodents ...
Science Daily

Unraveling the reward behavior: Mechanisms underlying the dopamine signaling pathway

Researchers discover that the phosphorylation of a newly identified protein kinase substrate downstream of the dopamine signaling pathway regulates the brain reward behavior. The nucleus accumbens, ...
EurekAlert!

Perception—but not expectation—of reward is altered in people with cocaine addiction

Researchers report October 25 in the journal Neuron that cocaine addiction disrupts the dopamine neurons that govern how we perceive and learn from rewards. Though people with cocaine addiction have ...
Science Daily

Perception--but not expectation--of reward is altered in people with cocaine addiction

Researchers report that cocaine addiction disrupts the dopamine neurons that govern how we perceive and learn from rewards. Though people with cocaine addiction have similar expectations of rewards ...