SYNGAP1 encephalopathy is a rare genetic disorder for which there is no treatment. It causes epilepsy, intellectual disability, psychomotor delay and, frequently, autism. It arises from mutations in ...

Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder is a rare, genetically determined developmental and epileptic encephalopathy characterized by early-onset refractory seizures and severe ...

The purpose of the CNC Epilepsy and Epilepsy Disorders Pillar is to foster collaborative research projects between basic and clinical scientists that will lead to better and improved approaches for ...

Psychiatric disorders (MD and/or AD) were detected in approximately 40% of patients with MTLE. Pharmacoresistant epilepsy was significantly linked with comorbid psychiatric disorders. Positive family ...

ORLANDO — Sleep disorders in people with epilepsy are linked to a significantly higher risk for sudden unexplained death in epilepsy (SUDEP) and all-cause mortality, new research shows. Marion Lazaj, ...

The study sought to evaluate the efficacy, safety, and tolerability of azetukalner, administered as an oral, adjunctive, once ...

Investigators led by Northwestern Medicine scientists have identified mutations in a gene coding for a key ion channel in the ...

Epilepsy affects more than 3 million people in the U.S., or about 1 percent of the population, and is one of the most common neurological disorders. Epilepsy can develop at any age, but is most common ...

In a large-scale study of electronic health records investigators determined the prevalence of functional seizures and characterized comorbidities associated with them. Functional seizures are sudden ...

Researchers demonstrated that individuals who had childhood epilepsy have an increased accumulation of brain amyloid later in life, potentially predisposing them to late-onset brain amyloid disorders, ...

Please provide your email address to receive an email when new articles are posted on . Among 2,214 persons with epilepsy, 7.5% had MDD, and 4% had generalized anxiety disorder. Those on valproic acid ...