New research reveals that ancient interbreeding between humans and Neanderthals shaped our modern human DNA - especially on the X chromosome.

Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human pangenome reference. Published ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

It is common knowledge that Down syndrome—a neurodevelopmental and neurodegenerative disorder with hallmark physical features and mild to moderate cognitive impairment—occurs when individuals have an ...

Mosaic trisomy 8 is a rare genetic condition caused by an extra chromosome. Sometimes called trisomy 8 mosaicism, this condition develops well before birth. It's a result of an abnormality in how ...

Men tend to lose the Y chromosome from some of their cells as they age — a process once thought to be harmless because the Y ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

The cells in our body are constantly fighting off the threat of cancer by repairing damaged DNA. In a new study, scientists investigate the structure of an elusive protein complex that plays a key ...