T cell lymphocytes play a central role in the adaptive immune response. They are an essential tool of adoptive cell therapy for the treatment of chronic viral infections and malignant diseases.

Using precise molecular techniques, including single-cell RNA sequencing, the team showed that this process is mediated in part by the effects of CD4 T cells on CD8 T cells – another subset of white ...

Researchers found that CD4+ T cells can be classified into 18 categories and 12 distinct gene programs, and that characteristic changes in CD4+ T cell profiles are associated with autoimmune disease, ...

Researchers have established a direct experimental link between inflammatory signals in the intestinal lining and the kind of ...

In this study, we revealed the pulmonary pathogen profiles of immunosuppressed ICU patients based on CD4+T-cell counts: the ...

A panelist discusses how CD4 counts serve as measures of immune system status that typically increase by about 200 in the first year of antiretroviral therapy. Although there can be laboratory ...

Whole brain radiotherapy and intrathecal injection of thiotepa, combined with systemic treatment for the primary tumor, to treat solid tumor leptomeningeal metastasis: A prospective, single center, ...

Certain levels of urinary CD4+ T lymphocytes in patients with ANCA-associated vasculitis have a 60% and 98% sensitivity and specificity, respectively, for predicting future renal flares. Urinary CD4+ ...

Scientists at Cincinnati Children's have identified how certain immune cells are molecularly programmed to respond faster ...