Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction. As professional antigen-presenting cells, they bridge innate sensing and durable ...

Researchers at Kobe University discovered an entirely new and unexpected mechanism by which the immune system can get rid of cells lacking molecules that identify them as part of the self in mice. The ...

The intersection of immunology and materials science is causing a paradigm change in the field of vaccine delivery. In the past, vaccinations relied on ...

Sepsis remains a major challenge in modern medicine, claiming millions of lives each year. For decades, clinical management ...

New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...

Nanovials are emerging as an accessible platform for performing single-cell functional screening leveraging standard instrumentation, such as flow cytometers and microfluidic single-cell sequencing ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Basal cell carcinoma has low immunogenicity. Tumor cells express Foxc1 protein (red), which suppresses HLA class I (green) in the tumor cells. Compromised antigen presentation ranks among the top ...

A common strep throat infection can trigger guttate psoriasis by altering the behavior of key immune cells, according to a ...