The voltage-dependent anion channel (VDAC) mediates the flow of metabolites and ions across the outer mitochondrial membrane of all eukaryotic cells. The open channel passes millions of ATP molecules ...
Figure 1: Structure of AMP-PNP–bound BtuCD EQNC. Given that the cytoplasmic concentration of ATP in live cells is in the millimolar range, visualizing the ATP-bound state of BtuCD was essential to ...
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